If you want to use Read&Write on a Terminal Server, you should use the Local MSI Install option.
To install on Terminal Server, you need to disable audio-redirection for the terminal server session. The Terminal Server will also need to have an Audio Card installed.
Each instance of Read&Write will need to use its own speech engine, so it can be quite memory intensive if a lot of users are using it on one server. Highlighting the text being read in the document will also be unsynchronized with the speech heard on the client PC due to latency in the screen redrawing.
Please Note: if Read&Write is installed locally on the computer and you are accessing a terminal server window, due to the way the text is presented in terminal server windows, Read&Write is unable access the text to read it from the terminal server window.